منابع مشابه
Liking, wanting, and the incentive-sensitization theory of addiction.
Rewards are both "liked" and "wanted," and those 2 words seem almost interchangeable. However, the brain circuitry that mediates the psychological process of "wanting" a particular reward is dissociable from circuitry that mediates the degree to which it is "liked." Incentive salience or "wanting," a form of motivation, is generated by large and robust neural systems that include mesolimbic dop...
متن کاملDrug wanting: behavioral sensitization and relapse to drug-seeking behavior.
Repeated exposure to drugs of abuse enhances the motor-stimulant response to these drugs, a phenomenon termed behavioral sensitization. Animals that are extinguished from self-administration training readily relapse to drug, conditioned cue, or stress priming. The involvement of sensitization in reinstated drug-seeking behavior remains controversial. This review describes sensitization and rein...
متن کاملIncentive sensitization by previous amphetamine exposure: increased cue-triggered "wanting" for sucrose reward.
We reported previously that an amphetamine microinjection into the nucleus accumbens enables Pavlovian reward cues in a conditioned incentive paradigm to trigger excessive instrumental pursuit. Here we show that sensitization caused by previous amphetamine administration also causes reward cues to trigger excessive pursuit of their associated reward, even when sensitized rats are tested in a dr...
متن کاملIncentive-sensitization and addiction.
The question of addiction concerns the process by which drug-taking behavior, in certain individuals, evolves into compulsive patterns of drug-seeking and drug-taking behavior that take place at the expense of most other activities, and the inability to cease drug-taking, that is, the problem of relapse. In this paper we summarize one view of this process, the "incentive-sensitization" view, wh...
متن کاملDecision Utility , Incentive Salience , and Cue - Triggered “ Wanting ” 24
addicts trying to quit, a cue for the addicted drug might trigger urges that rise to compulsive levels of intensity despite prior commitments to abstain, leading to the decision to relapse into taking the drug again. Normal or addicted, the urge and decision may well have been lacking immediately before the cue was encountered. Th e decision to pursue the cued reward might never have happened i...
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ژورنال
عنوان ژورنال: Psychopharmacology
سال: 2004
ISSN: 0033-3158,1432-2072
DOI: 10.1007/s00213-003-1602-z